WebApr 10, 2024 · Cisplatin (40 mg/m2) was delivered weekly during external beam radiation therapy and once with brachytherapy. Among 26 eligible patients with para-aortic metastasis or high common iliac involvement, 16 (62%) patients had a complete response for both local and nodal disease. However, the acute and late grade 3/4 toxicity rate was 81% and 40% ... WebAlternative protocols like weekly 40 mg/m2 have been used in an attempt to reduce toxicities. The main objective of the present study is to identify the dose intensities and toxicities of weekly cisplatin in patients treated in a tertiary centre over a 12 month period.
Cisplatin Intravenous: Uses, Side Effects, Interactions ... - WebMD
WebFeasibility and efficacy of CRT with weekly cisplatin 40 mg/m2 were suboptimal in this analysis. However, the prospects of weekly cisplatin may be its more suitable … WebWeekly administration of cisplatin is therefore feasible in patients receiving a continuous course of irradiation. The high relapse rate observed in responding patients indicates the need for evaluation of the efficacy of combination chemotherapy in the adjuvant or neo-adjuvant setting. Publication types Clinical Trial Clinical Trial, Phase I chirp books reviews
Concurrent radiation and weekly cisplatin for non-small-cell lung ...
WebThe cumulative linear quadratic equivalent dose (EQD2) was 62 to 65 Gy prescribed at point A. Cisplatin was administered weekly at a dose of 40 mg/m(2) for 5 courses. Results: Between March 2008 and January 2009, 72 patients from 25 institutions were enrolled, and 71 patients were eligible and evaluable for compliance and severe toxicity. WebSep 20, 2024 · This study is being done to find out if low-dose cisplatin given weekly together with radiation therapy is the same or better than high-dose cisplatin given … WebCERVICAL CANCER CHEMOTHERAPY • Cisplatin weekly preferred ... Ovarian Pembrolizumab 200mg IV q 21D or 400mg IV q 42D Cervical, Endometrial, Ovarian Cisplatin IV 40mg/m2 (dose cap 70mg) weekly with concurrent XRT Cervical, Endometrial Carboplatin IV AUC 2 weekly with concurrent XRT (if cisplatin intolerant, ... chirp book store