Dibutyryl-cyclic amp
WebApr 29, 1983 · In the presence of 7 mM glucose, dibutyryl cyclic AMP induced electrical activity in otherwise silent mouse pancreatic B cells. This activity was blocked by cobalt or D600, two inhibitors of Ca 2+ influx. Under similar conditions, dibutyryl cyclic AMP stimulated 45 Ca 2+ influx (5-min uptake) in islet cells; this effect was abolished by cobalt … WebDibutyryl-cAMP (DB-cAMP) is a cell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (e.g. protein kinase A) and inhibits phosphodiesterases. …
Dibutyryl-cyclic amp
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WebCyclic dibutyryl AMP C18H24N5O8P CID 2460 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... WebWith dibutyrl cyclic AMP (dbcAMP) a dose-dependent increase was seen with 0.5-5 mM concentrations with no further effect of higher concentrations. Time course studies were …
WebThe functions and biosynthesis of sterols have been effective targets for fungal control in different areas, including pharmaceutical and agricultural applications. Fungi are among the organisms that synthesize sterols, principally ergosterol. In this paper, the effect of dibutyryl-cAMP (db-cAMP) on … WebIn dibutyryl cyclic AMP-induced “differentiated” neuroblastoma cells NBA 2 (1), the DNA synthesis decreased by 80 ± 3.5% of control, whereas RNA and protein synthesis increased by 37 ± 8.0 and 19 ± 4.1%, respectively (Prasad et al., 1972c).
WebWhen dibutyryl cyclic AMP, a derivative resistant to degradation by phosphodies-terase and presumably capable of penetrating the cell more readily, became available, investigation of the effect of this agent on contractility was soon undertaken. Several workers have demonstrated apparent augmentation of contractility by dibutyryl cyclic AMP (24 ... WebDibutyryl cyclic monophosphate (dBcAMP) has been shown to inhibit growth, and alter the morphology of astrocytes. However, the potential contribution of its hydrolytic product, butyrate, in inducing some of the changes that have been attributed to dBcAMP, is not clear. DNA, RNA, and purine synthesis were therefore studied in primary astrocyte cultures …
WebJul 23, 1984 · We have examined the effects of dibutyryl-cyclic AMP (dBcAMP) on the organization and expression of filamentous proteins in astroglia. The drug produced several effects on astrocytes grown in primary cultures. Cultures ceased to grow, and cells changed shape to a contracted form, displaying thin cyt …
WebJan 6, 2024 · Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs. Hei, … shark stratos cordless iz420uktWebThe infusion of dibutyryl cyclic 3',5' AMP at a rate of 3 mg/hr into thyroparathyroidectomized rats leads to changes in calcium, phosphate, and hydroxyproline excretion, and calcium and phosphate concentrations in plasma that are qualitatively similar to those induced by parathyroid hormone given at a rate of 5 mug/hr. The effect of … population density geography chart nameWebtion, dibutyryl cyclic AMP can be used as a cell-permeant activator of cyclic AMP-dependent functions.These CAMP- related agents block or inhibit activation of several effector functions of human neutrophils including superoxide gener- ation and lysosomal enzyme release (39, 40). However, little population density for zip code 99362WebDibutyryl-cAMP activates cAMP-dependent protein kinases. It induces morphological differentiation of astrocytes and neurite outgrowth in PC12 cells. Dibutyryl cyclic-AMP … population density for zip code 88130WebOct 10, 1976 · A single injection of either isoproternol or N6, O2'-dibutyryl adenosine 3':5'-monophosphate (dibutyryl cyclic AMP) results in an inhibition in the rate of [3H]thymidine incorporation into DNA of differentiating cardiac muscle of the neonatal rat. This inhibition is not due to substantially altered cellular uptake or catabolism of [3H]thymidine. population density frederictonWebAddition of dibutyryl cyclic AMP to the medium does not affect labeling of either large or middle T antigens in wild-type- or mutant-infected cells. Thus no differences are … shark stratos cordless vacuum cleanersWebIn cancer cells, endogenous or therapy-induced DNA damage leads to the abnormal presence of DNA in the cytoplasm, which triggers the activation of cGAS (cyclic GMP-AMP synthase) and STING (stimulator of interferon genes). STAT2 suppresses the cGAMP-induced expression of IRF3-dependent genes by bindi … shark stratos commercial