Web21 de mar. de 2024 · Size: 669 amino acids Molecular mass: 72433 Da Protein existence level: PE1 Quaternary structure: Isoform 2 interacts (via ODD domain) with VHL (via beta … WebEpididymal fat weight differences between genotypes persisted when epididymal fat was expressed as a percentage of overall body weight (5.3% ± 0.2% in Hif1a F/F mice overall vs. 4.6% ± 0.1% in Hif1a −/− hep mice overall; P = 0.034 for genotype effect determined by using two-way ANOVA).

Acetyl-CoA Carboxylase Antibody Cell Signaling Technology

WebPHD1 (Egln2), PHD-2 (Egln1), and PHD3 (Egln3) are members of the Egln family of proline hydroxylases. They function as oxygen sensors that catalyze the hydroxylation of HIF on prolines 564 and 402, initiating the first step of HIF degradation through the VHL/ubiquitin pathway (1,2). PHD1 is highly expressed in a wide array of tissues whereas ... WebThere are several isoforms of the HIF α subunit (2). Studies have found that HIF-1α and HIF-2α expression is increased in some human cancers (2). HIF-1α has both pro- and … fishy swimming in the water

STUB1/CHIP is required for HIF1A degradation by chaperone-mediated ...

WebAcetyl-CoA carboxylase (ACC) catalyzes the carboxylation of acetyl-CoA to malonyl-CoA (1). It is the key enzyme in the biosynthesis and oxidation of fatty acids (1). In rodents, the 265 kDa ACC1 (ACCα) form is primarily expressed in lipogenic tissues, while 280 kDa ACC2 (ACCβ) is the main isoform in oxidative tissues (1,2). WebMolecular Vision. 2014-01-01 [PMID: 25593505] (WB, Human) Details: HIF-2 alpha/EPAS1 antibody used for WB on lysates of HLE-B3 cells, a human lens epithelial cell line immortalized by the SV-40 virus, treated or not with HIF-2 alpha translation inhibitor (CAS882268-69-1) at 0.5, 5 and 50 uM concentrations (Figure 11A) WebDisclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation … fishy tails restaurant