Phosphohistidine phosphatase sixa
WebThe sixA gene encodes a phosphohistidine phosphatase that specifically removes the phosphoryl group from the His717 residue of ArcB . [More information is available at … WebJan 1, 2024 · A secondary lymphoid organ, Spleen hosts highly dormant hematopoietic stem cells. Molecular pathways essential for splenic HSC maintenance, and regulating their function in the spleen at a steady state, remain elusive.
Phosphohistidine phosphatase sixa
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WebJan 1, 2024 · We show that the phosphatase SixA dephosphorylates the phosphocarrier protein NPr and that the reaction proceeds through phosphoryl transfer from a histidine on NPr to a histidine on SixA. In addition, we show that Escherichia coli lacking SixA are outcompeted by wild-type E. coli in the context of commensal colonization of the mouse … WebFeb 10, 2024 · Our results suggest a model in which SixA removes phosphoryl groups from the nitrogen-related phosphotransferase system by acting on NPr. This work uncovers a new role for the phosphohistidine phosphatase SixA and, through factors that affect SixA expression or activity, may point to additional inputs that regulate the nitrogen-related ...
Web(GenBank) phosphohistidine phosphatase SixA. KO: K08296 : phosphohistidine phosphatase [EC:3.1.3.-] Organism: dht Dolichospermum heterosporum. Brite: KEGG Orthology (KO) [BR:dht00001] 09190 Not Included in Pathway or Brite 09191 Unclassified: metabolism 99980 Enzymes with EC numbers WebMar 1, 2002 · Taking all these results together, we conclude that SixA exhibits a phosphohistidine phosphatase activity, of which the phospho-HPt domain of ArcB is a substrate. Figure 7. Open in figure viewer PowerPoint. β-Galactosidase activity expressed by a set of transformants of DZ225 and DZS225. A. DZ225 was transformed with the …
Webphosphohistidine phosphatase SixA : Closest Orthologs (e-value cutoff: 1e-4) species: id: gene: e-value: identity (len) annotation: M. bovis AF2122 / 97: Mb1307c-5e-63: 71.52% (158) hypothetical protein Mb1307c: M. gilvum PYR-GCK: Mflv_2254-7e-51: 58.14% (172) putative phosphohistidine phosphatase, SixA: M. tuberculosis H37Rv: WebNov 27, 2024 · SixA, a well-conserved protein found in proteobacteria, actinobacteria, and cyanobacteria, is the only reported example of a bacterial phosphohistidine phosphatase. …
WebNov 27, 2024 · SixA, a well-conserved protein found in proteobacteria, actinobacteria, and cyanobacteria, is the only reported example of a bacterial phosphohistidine phosphatase. …
chloe rahilly andover maWebResearch in the field of protein-bound phosphohistidine phosphorylation has been hampered by the difficulties in analysis and detection of phosphohistidine. Therefore a screening method was developed primarily for the analysis of phosphohistidine phosphatase 1 (PHPT1) activity. Methods. A highly positively charged substrate, Ac-Val … chloe ralph smithWebNov 10, 2006 · The structure of phosphohistidine phosphatase (PHPT1) has been determined to a resolution of 1.9Å using multiple-wavelength anomalous dispersion methods and Histidine 53 is proposed to play a major role in histidine dephosphorylation based on these observations and previous mutational studies. chloe puppy dog palsWebFeb 20, 2002 · This histidine phosphatase activity is directed towards the phosphotransmitter domain of the bacterial hybrid histidine kinase. SixA consists of 161 … chloe rattan bucket bagWebNov 10, 2006 · SixA shows structural homology to the well studied family of arginine-histidine-glycine (RHG) phosphatases but no sequence homology to PHPT1. Mammalian phosphohistidine phosphatase (PHPT1) was first identified and characterized as a 14-kDa protein in 2002 (7, 8). grass valley long range shootingWebphosphatase. A single protein target of SixA has been reported to date: the Esche-richia coli histidine kinase ArcB. The present work analyzes an ArcB-independent growth defect of a … chloe rahcel headphonesWebExpression profile; Y-axis: expression values, x-axis: tissues/treatments. Red dots: average expression, green dots: expression from individual microarray/RNAseq experiments. chloe raffles city